Gabor Sneaker

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Gabor Sneaker
height of heel
<i>in gr.</i> <b>in grams.</b> <i>37 ca.</i> <b>37 ca.</b> <i>25 cm</i> <b>25 cm</b> uppers
suede interior material
textiles style
athletic applications
stitchings special features
in shoe width g (= far) shutter
lacing shoe lace
round insole material
manager insole features
removable outsole material
synthetic outsole profile
distinctive shoe height
low shoe-wide
far height of heel
<i>in gr.</i> <b>in grams.</b> <i>37 ca.</i> <b>37 ca.</b> <i>25 cm</i> <b>25 cm</b> uppers
suede interior material
textiles style
athletic applications
stitchings special features
in shoe width g (= far) shutter
lacing shoe lace
round insole material
manager insole features
removable outsole material
synthetic outsole profile
distinctive shoe height
low shoe-wide
Gabor Sneaker Gabor Sneaker Gabor Sneaker Gabor Sneaker Gabor Sneaker
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The placenta is crucial to keeping your baby alive and well during pregnancy. It is an organ attached to the lining of the womb that delivers oxygen and nutrients to the growing baby.

The placenta is a large organ that develops during pregnancy. It is attached to the wall of the uterus, usually at the top or side. The umbilical cord connects the placenta to your baby.

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Text description provided by the architects. The Interlace is located on an elevated eight-hectare site, bounded by Alexandra Road and the Ayer Rajah Expressway, amidst the verdant Southern Ridges of Singapore. With about 170,000m2 of gross floor area, the development will provide 1,040 apartment units of varying sizes with extensive outdoor spaces and landscaping. The site completes a green belt that stretches between Kent Ridge, Telok Blangah Hill and Mount Faber Parks.

Designed by Ole Scheeren, partner of the Office for Metropolitan Architecture (OMA), The Interlace breaks away from Singapore’s standard typology of isolated, vertical apartment towers and instead explores a dramatically different approach to tropical living: an expansive interconnected network of living and communal spaces integrated with the natural environment. Thirty-one apartment blocks, each six-stories tall and identical in length, are stacked in a hexagonal arrangement to form eight large-scale open and permeable courtyards. The interlocking blocks form a vertical village with cascading sky gardens and both private and public roof terraces.

The design capitalizes on the generous size of the site and further maximizes the presence of nature by introducing extensive roof gardens, landscaped sky terraces and cascading balconies. Above- ground vehicular circulation is minimized, liberating large green areas within the development. The Interlace incorporates sustainability features through careful environmental analysis of sun, wind, and micro-climate conditions on site and the integration of low-impact passive energy strategies.

Within the ischemic cerebrovascular bed, there are two major zones of injury: the core ischemic zone and the “ischemic penumbra” (the term generally used to define ischemic but still viable cerebral tissue).

In the core zone, which is an area of severe ischemia (blood flow below 10% to 25%), the loss of oxygen and glucose results in rapid depletion of energy stores. Severe ischemia can result in necrosis of neurons and also of supporting cellular elements (glial cells) within the severely ischemic area.

Brain cells within the penumbra, a rim of mild to moderately ischemic tissue lying between tissue that is normally perfused and the area in which infarction is evolving, may remain viable for several hours. That is because the penumbral zone is supplied with blood by collateral arteries anastomosing with branches of the occluded vascular tree (see inset). However, even cells in this region will die if reperfusion is not established during the early hours since collateral circulation is inadequate to maintain the neuronal demand for oxygen and glucose indefinitely. In this example, the ischemic penumbra is shown as a rim of tissue surrounding the severely ischemic core lying within the vascular territory of the pre-Rolandic branch of the left middle cerebral artery. The Rolandic artery is occluded by a thromboembolus. The extent of the penumbra varies directly with the number and patency of collateral arteries.

The penumbra is where pharmacologic interventions are most likely to be effective. However, it may also be possible to salvage cells within the severely ischemic core zone. Although severe ischemia kills selectively vulnerable neurons, glial cells may be spared if blood flow is restored early. Therefore, timely recanalization of the occluded vessel should theoretically restore perfusion in both the penumbra and in the severely ischemic core. Partial recanalization should markedly reduce the size of the penumbra as well.

Credits Acute Ischemic Stroke: New Concepts of CareThe presentation of this content is made possible with permission from Genentech, Inc .Copyright 1998-1999 Genentech Inc., all rights reserved. Content may not be reproduced without permission.

Credits

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This project is supported in part by the NIH Specialized Programs of Translational Research in Acute Stroke (SPOTRIAS) Network, and NINDS grant 3P50NS055977 to Washington University in St. Louis School of Medicine and UT Southwestern Medical Center.

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Sierra Edition

Cocktail is a general purpose utility for macOS that lets you clean, repair and optimize your Mac. It is a powerful digital toolset that helps hundreds of thousands of Mac users around the world get the most out of their computers every day.

The application serves up a perfect mix of maintenance tools and tweaks, all accessible through a clean and easy to use interface. Cocktail's features are arranged into five categories that helps you manage various aspects of your computer. It also comes with an automatic Pilot mode that allows you to simply press a button and relax, knowing that Cocktail will take care of the rest.

Cocktail is installed at more than 250 000 computers world wide. The largest part being private individuals, but Cocktail can also be found at large international companies, educational institutions or newspapers.

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